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Symbol
Name
ID
Jak1
Janus kinase 1
MGI:96628
Phenotype annotations related to immune system
Darker colors indicate more annotations
Human Phenotypes
Subacute progressive viral hepatitis
Disease(s) Associated with JAK1
hepatocellular carcinoma

Mouse Phenotypes
small thymus
decreased thymocyte number
enlarged spleen
ear inflammation
abnormal lymphopoiesis
abnormal B cell differentiation
arrested B cell differentiation
abnormal T cell differentiation
increased double-negative T cell number
increased plasma cell number
decreased B cell number
abnormal plasma cell morphology
increased IgA level
increased IgG1 level
increased IgG2a level
increased IgM level
increased immunoglobulin level
increased anti-nuclear antigen antibody level
skin inflammation
Availability Mouse Genotype
Jak1tm1Rds/Jak1tm1Rds
Jak1M1Mhda/Jak1+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory